Abstract
In the present study, we aimed to evaluate the prevalence of dyslipidemia in students from different ethnic groups in Xinjiang. It is an observational, cross-sectional study. The sample of 7096 students aged 21–25 years was randomly selected from the clinic of Xinjiang Medical University. Baseline data, serum concentration of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and fasting plasma glucose (FPG) were reported. The prevalence of changes in lipid profile according to Body mass index (BMI) in three ethnic groups was calculated. Compared with Han and Uygur students, TC, LDL-C, TG and FPG levels were lower in kazakh sutdents, while HDL-C level was lower in Uygur students. The prevalence of high TC change was higher in Uygur students, and high LDL-C change was higher in Han students. The prevalence of low HDL-C change was higher in Uygur students, and high TG change was lower in Kazakh students. The prevalence of high TC, LDL-C, TG and low HDL-C changes was observed in normal weight, overweight and obesity groups according to the nutritional status by BMI among students of each ethnic group. The present study demonstrated the prevalence of dyslipidemia in students from different ethnic groups, and enriched the limited data on the early prevention and treatment of dyslipidemia and cardiovascular diseases in Xinjiang medical students crowd.
Highlights
Dyslipidemia is increasingly prevalent in all age groups, and the incidence tends to be younger[11]
total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), TG and fasting plasma glucose (FPG) levels were lower in Kazakh students than other two groups, and high density lipoprotein cholesterol (HDL-C) levels were lower in Uygur students than Han and Kazakh students
The prevalence of high low density lipoprotein (LDL)-C change was significantly higher in Han students (P = 0.003, Table 2), and the prevalence of low high density lipoprotein (HDL)-C change was significantly higher in Uygur students (P < 0.001, Table 2)
Summary
Dyslipidemia is increasingly prevalent in all age groups, and the incidence tends to be younger[11]. Bogalusa Heart Study reported that more than 70% of children with adverse lipid profiles are prone to dyslipidemia in adult life[14]. A study conducted on individuals from two regions of Argentina, aged 7–14 years old, revealed the prevalence of high TG was 28.8% and 3.5% and low HDL was 30% and 5.5%15. Another study on the Korean students aged 10–18 years old, indicated that the morbidity of dyslipidemia in girls and boys was 21.7% and 25.2%, respectively[16]. Epidemiologic surveys of cardiovascular disease (CVD) precursors in children have showed that differences in lipid and lipoprotein levels among cultures and ethnic groups occur early in childhood[18,19]. We aimed to establish the prevalence of dyslipidemia in college students from different ethnic groups and to evaluate its association with the nutritional status
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