Abstract
Dyslipidemia is considered a significant modifiable risk factor for type-2 diabetes mellitus (T2DM) and has become one of the emerging health problems throughout the world. In Bangladesh, data on dyslipidemia among newly diagnosed T2DM patients are comparatively inadequate. This study aimed to evaluate the prevalence of dyslipidemia and its associated risk factors in newly diagnosed T2DM patients. This cross-sectional study was conducted by a well-structured questionnaire from 132 newly diagnosed type-2 diabetic patients attending the Mujibur Rahman Memorial Diabetic Hospital in Kushtia, Bangladesh. Data regarding socio-demographic, anthropometric, fasting blood glucose, total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were collected from all the respondents. The association between dyslipidemia and its associated factors was analyzed using the multivariate logit regression model. The findings suggest that the prevalence rate of dyslipidemia was 75.7% in female and 72.6% in male T2DM patients. The odds of having dyslipidemia were 1.74 (95% Cl: 1.58-1.87) times significantly higher in female (p<0.001). The other factors associated with dyslipidemia encompassed age between 30-39 years (OR: 2.32, 95% CI: 1.97-2.69), obesity (OR: 2.63, 95% CI: 2.27-2.90), waist circumferences of male ≥90 and female ≥80 (OR: 1.65, 95% CI: 1.59-1.89), hypertensive patients (OR: 1.51, 95% CI: 1.45-1.74), physically inactive (OR: 3.25, 95% CI: 1.84-4.68), and current smoker or tobacco user (OR: 1.93, 95% CI: 1.85-2.13). This study concluded that the high prevalence of dyslipidemia was found among newly diagnosed type-2 diabetes patients and associated with gender, age, BMI, waist circumference, poor physical activity, and smoking, or tobacco use. This result will support increase awareness of dyslipidemia and its associated risk factors among type-2 diabetes patients.
Highlights
Diabetes mellitus (DM) is a chronic disease condition associated with hyperglycemia resulting from an imbalance in insulin secretion and insulin action or cooperation of [1, 2]
Several metabolic syndromes (MetS) including dyslipidemia, hyperglycemia, and hypertension become a channel to exacerbating cardiovascular disease (CVD) risk factors in type-2 diabetes mellitus (T2DM) patients [4, 5]
The results shows that patients with a higher Body mass index (BMI) were more likely to dyslipidemia disease, where obesity is associated with 2.63 times increased odds than underweight (p
Summary
Diabetes mellitus (DM) is a chronic disease condition associated with hyperglycemia resulting from an imbalance in insulin secretion and insulin action or cooperation of [1, 2]. Of all cases of diabetes, more than 90% are detected as type-2 diabetes mellitus (T2DM) around the world [3]. Several metabolic syndromes (MetS) including dyslipidemia, hyperglycemia, and hypertension become a channel to exacerbating cardiovascular disease (CVD) risk factors in T2DM patients [4, 5]. Metabolic syndrome (MetS) comprises several situations: elevated glucose and blood pressure level and abnormal cholesterol or triglyceride levels [6]. The MetS is recognized by a condition whereby the body’s cells cannot take up glucose from the blood [7]
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