Abstract
BackgroundThis study was performed to assess the prevalence of dry eye syndrome and diabetic retinopathy (DR) in type 2 diabetic patients and their contributing factors.Methods199 type 2 diabetic patients referred to Yazd Diabetes Research Center were consecutively selected. All Subjects were assessed by questionnaire about other diseases and drugs. Dry eye syndrome was assessed with Tear break up time tests and Schirmer. All the subjects underwent indirect ophthalmoscopy and retinal color photography. DR was graded according to early Treatment Diabetic Retinopathy (ETDRS) criteria.ResultsOf 199 subjects, 108 patients (54.3%) suffer from dry eye syndrome. Although dry eye syndrome was more common in older and female patients, this association was not significant. But there was significantly association between dry eye syndrome and duration of diabetes (P = 0.01). Dry eye syndrome was more frequent in diabetic patients with DR (P = 0.02). DR was found in 140 patients (70.35%), which included 34 patients (17.1%) with mild non proliferative DR (NPDR), 34 patients (17.1%) with moderate NPDR, 22 patients (11.1%) with severe NPDR and 25 patients (25.1%) with proliferative DR (PDR). There were significant relation between age, sex and duration of diabetes and DR.ConclusionIn this study the prevalence of dry eye syndrome was 54.3%. Diabetes and dry eyes appear to have a common association. Further studies need to be undertaken to establish an etiologic relationship. However, examination for dry eye should be an integral part of the assessment of diabetic eye disease.
Highlights
This study was performed to assess the prevalence of dry eye syndrome and diabetic retinopathy (DR) in type 2 diabetic patients and their contributing factors
This study suggests that tear film break up time (TBUT) should be a routine ophthalmologic test in diabetic patients [10]
The condition was confirmed by ocular surface dye staining pattern with fluorescein, tear film break up time (TBUT) and Schirmer test, according to American Academy of Ophthalmology by a specialist [11]
Summary
This study was performed to assess the prevalence of dry eye syndrome and diabetic retinopathy (DR) in type 2 diabetic patients and their contributing factors. Problems involving the ocular surface, dry eyes in particular, have been reported in diabetic patients [1]. These patients suffer from a variety of corneal complications including superficial punctuate keratopa-. Dry eye can lead to vision deficit, scarring and perforation of the cornea and secondary bacterial infection. If this syndrome is diagnosed at first stage and treated, would be protected from its complications [2]. Studies to evaluate the prevalence of dry eye syndrome in type 2 diabetic patients are lacking. We evaluated prevalence of dry eye syndrome in type 2 diabetic patients
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