Prevalence of drug-resistant uropathogenic bacteria in canines in the city of Merida, Yucatan

Abstract

Antibiotic treatment is key to the improvement of canine patients with urinary tract infections; however, the irrational use of antimicrobials has led to the emergence of resistance mechanisms in uropathogenic bacteria. The objective of the study was to identify the bacteria present in urine cultures from canines in the state of Yucatán, determine their sensitivity to antibiotics, the prevalence of resistance to methicillin (MR) and production of extended-spectrum beta-lactamase (ESBL). Identification and sensitivity to antibiotics were performed using the MicroScan commercial kit and the Kirby-Bauer technique. MR was determined by sensitivity to oxacillin/cefoxitin and ESBL production through synergy techniques with beta-lactamase inhibitors. The most frequently isolated bacteria was Proteus mirabilis and the antibiotic with the highest percentage of resistant strains was norfloxacin; 30.2% of the Enterobacterales strains manifested ESBL production and 39.4% of the Staphylococcus spp. showed MR. The development of drug resistance is an important problem, only the knowledge about the prevalence of these uropathogenic bacteria and their drug-resistant strains in our state will allow us to propose effective treatment protocols.