Abstract

Background: Dissociative symptoms have been reported to result from issues such as substance use. However, there is limited knowledge on the relationship between methamphetamine use and dissociative symptoms, and only a few studies have been conducted on this issue. Objectives: Given little knowledge on the relationship between methamphetamine use and dissociative symptoms, in particular dissociative disorders, the present study was done to investigate the prevalence of dissociative experiences and dissociative disorders in methamphetamine users in Shahid Beheshti hospital of Kerman City, Kerman Province, Iran. Methods: In this descriptive cross-sectional study, two groups of subjects, including methamphetamine users (N = 50) and controls (N = 51), were randomly selected from the individuals referring to Shahid-Beheshti Hospital, Kerman City, from September 2016 to March 2018. After validating the diagnosis of methamphetamine use via methamphetamine positive-urine test, the Dissociative Experiences Scale (DES) and dissociative disorders interview schedule-DSM5 (DDIS) were employed to assess dissociative experiences and disorders, respectively. Next, the Positive and Negative Syndrome Scale (PANSS) was utilized for the determination of positive and negative symptoms of psychosis in the case group. Finally, the chi-square test and t test were applied for comparing the study groups using SPSS version 20 software. Results: Our findings revealed that the mean score of dissociative symptoms was 15.3 in methamphetamine users. The mean score of depersonalization/derealization subscale of DES, as a dissociative experience, was higher in the case group (P < 0.01). The experience of possession, as a dissociative experience, was recorded in 17 methamphetamine users, while 18 (36%) methamphetamine users were diagnosed with dissociative disorder. Furthermore, a significant correlation was found between the DES score and positive symptoms in methamphetamine users (P < 0.05). Conclusions: According to the findings of the present study, it can be concluded that methamphetamine induces dissociative psychosis in methamphetamine users.

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