Prevalence of different forms of neuropathies in type 2 diabetes patients attending a tertiary care hospital in Central Gujarat: A hospital based cross sectional study

Abstract

Introduction: Diabetic neuropathy (DN) is commonest forms of complications observed in type 2 diabetes patients. Due to variations in clinical and electrophysiological diagnostic criteria for polyneuropathies, prevalence of diabetic neuropathy varies in different studies. We used only (Electro diagnostic) EDX criteria for diagnosis of neuropathies in present study. Aim and Objectives: To estimate prevalence of diabetic neuropathy; viz, mononeuropathy, polyneuropathy and mononeuropathy with coexistent polyneuropathy in population of subjects with type 2 diabetes mellitus. Materials and Methods: It was a cross sectional study where total 53 diabetic subjects (30 male, 23 female) in age range 30-60 years were electrophysiologically evaluated for neuropathies during January 2013 to December 2015. Routine and specialized Nerve conduction studies were adopted for evaluation. Data was acquired and stored in Microsoft excel and analyzed using graph pad prism software. Results: Overall prevalence of diabetic neuropathy (DN) was 54.71%. Prevalence of other forms viz. Polyneuropathy only, mononeuropathy only and mononeuropathy with coexistent polyneuropathy are 30.18%, 16.98% and 7.54 % respectively. Median neuropathy at wrist was the only form of mononeuropathy observed in these cases. Severity of mononeuropathy was observed more in diabetes without polyneuropathy cases. Conclusion: Prevalence of different forms of neuropathies observed in present study is similar to previous studies. We observed more severe mononeuropathy in diabetes without polyneuropathy cases. Palm wrist comparison study must be part EDX evaluation in these cases. Keywords: Diabetes mellitus, Diabetic polyneuropathy, Nerve conduction study.