Abstract
Abstract Background Diabetic Ketoacidosis (DKA) is one of the most serious acute complications of Diabetes Mellitus (DM) and the leading cause of morbidity and mortality in young adults with type 1 diabetes. The mortality rate for DKA ranges from 2 to 5% in developed countries and 6 to 24% in developing countries. Even though many DKA patients were seen in emergency unit of Ethiopian hospitals and health centers, little is known about precipitating factors and clinical-laboratory features of DKA among Ethiopian patients and information is scant to promote better health service to prevent mortality due to DKA. So the aim of this study is to assess the prevalence and associated risk factors of DKA in newly diagnosed Type 1 Diabetic patients in Dilla University Referral Hospital (DURH) from September 9th/2017-May 30th/2019. Methods Quantitative institutional based study was conducted among 421 newly diagnosed type one diabetic patients. Data was double entered from the paper-based abstraction sheet into Epi info version 7 and exported to SPSS version 20 for analysis. A descriptive analysis was performed. Bivariate and multivariate logistic analysis was done to identify factors associated with the magnitude of Keto acidosis. Variables with p-value less than 0.05 were declared as having significant association between factors and dependent variable. Result The magnitude of Diabetic Keto Acidosis (DKA) in newly diagnosed patients with type one diabetic Mellitus (T1DM) was found to be 38%. The significant predictors of Diabetic Keto Acidosis (DKA) among newly diagnosed patients with type one diabetic Mellitus (T1DM) were young age of the adult, family history of diabetes and infection prior to onset of Diabetic Keto Acidosis (DKA). Conclusion The overall magnitude of Diabetic Keto Acidosis (DKA) in adults with newly diagnosed type 1 diabetes is high. In particular, adults between 18-25 years of age have a high risk of Diabetic Keto Acidosis (DKA) at onset of diabetes mellitus. Young Age, first degree relatives with Diabetic Mellitus (DM) and infection prior to Diabetic Keto Acidosis (DKA) are found to be the significant explanatory variable of Diabetic Keto Acidosis (DKA) in primary onset of T1DM.
Highlights
A normal blood sugar level for a person who has not been diagnosed with diabetes should be 80-99 mg/dL when they have not eaten for more than two hours
An institution based cross sectional study was conducted from September 9th/2017-May 30th/2019 on 421 randomly selected newly diagnosed patients with type 1 diabetes mellitusthat were admitted in medical emergency in Dilla University Referral Hospital (DURH) from September 2017 till 1st May 2019 G.C
A total of 421 charts of newly diagnosed patients with type 1 diabetes mellitus between September 2017 and May 2019 were reviewed of 421 adults (21.1%) was orthodox Christian, (21.4%) Muslims and 185 (43.9%) were protestants
Summary
A normal blood sugar level for a person who has not been diagnosed with diabetes should be 80-99 mg/dL (milligrams per deciliter) when they have not eaten for more than two hours. Diabetes is a disease that affects blood sugar management in the human body, it means the amount of glucose or sugar in your blood typically remains too high and exceeds blood sugar levels that are considered normal. Worldwide estimates project that in 2030 the greatest number of individuals with diabetes will be 45-64 years of age [1,2]. World health organization (WHO) estimates the number of cases of diabetics in Ethiopia to be about 800,000 in 2000 and by this protestation it would increase to about 1.8 million by the year 2030 [2]. The aim of this study is to assess the prevalence and associated risk factors of DKA in newly diagnosed Type 1 Diabetic patients in Dilla University Referral Hospital (DURH) from September 9th/2017-May 30th/2019
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
