Abstract

Objective: This study aimed to estimate the prevalence of diabetes mellitus (DM) and impaired fasting glucose (IFG) in a Kazakh population aged ≥18 years living in the YiLi District of Xinjiang, China and to evaluate the associated risk factors of diabetes. Methods: Randomly selected adults, living for at least 6 months in the YiLi District in Xinjiang had their clinical characteristics and standard blood chemistries measured. DM and IFG were defined according to WHO 1999 criteria. The adjusted odds ratio (ORs) and 95% confidence intervals were calculated for the association of diabetes risk factors in multivariate logistic regression models. Results: A total of 3919 subjects were randomly selected. The age-and gender-standardized prevalence of DM and IFG were 5.9% and 10.0%, respectively. The prevalence of DM and IFG increased with age and BMI. Prevalence of 7.4%, 12.2% in males and 4.9%, 8.6% in females for DM and IFG. Compared by sex, prevalence of DM and IFG was higher in males. Prevalence of 3.4%, 8.1% in normal, 6.7%, 11.9% in overweight and 12.0%, 13.0% in obesity for diabetes and IFG. In the multivariable logistic models, male sex, older age, unmarried, overweight, obesity, hypertension, triglycerides and smoking were all significantly associated with an increased risk of diabetes. Conclusions: The prevalence of DM and IFG among minorities was lower than the overall national level both in men and women (9.7% in total, 10.6% in males, 8.8% in females), and also lower than among the Han ethnicity (9.26%) which predominates in China today.

Highlights

  • Diabetes mellitus (DM) is rapidly becoming one of the most common non-communicable diseases globally [1]

  • With China’s economic growth, population aging, nutritional transition and urbanization, especially in economically underdeveloped areas such as Xinjiang, there have been few studies of the pattern of the DM epidemic among the Han nationality and its major risk factors, especially since no studies have included the Xinjiang minority epidemic of DM and impaired fasting glucose (IFG) in a rural area. To address this gap in knowledge, we conducted a study aimed to estimate the prevalence of DM and IFG and to evaluate the associated risk factors of diabetes in the Kazakh adult population

  • The results of the present study reveal that the standardized prevalence of DM among Kazakh adult population living in Xinjiang is 5.9% (7.4% in males and 4.9% in females)

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Summary

Introduction

Diabetes mellitus (DM) is rapidly becoming one of the most common non-communicable diseases globally [1]. With China’s economic growth, population aging, nutritional transition and urbanization, especially in economically underdeveloped areas such as Xinjiang, there have been few studies of the pattern of the DM epidemic among the Han nationality and its major risk factors, especially since no studies have included the Xinjiang minority epidemic of DM and IFG in a rural area. To address this gap in knowledge, we conducted a study aimed to estimate the prevalence of DM and IFG and to evaluate the associated risk factors of diabetes in the Kazakh adult population

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