Prevalence of Diabetes and Associated Factors in the Uyghur and Han Population in Xinjiang, China.

Haiying Gong,Li Pan,Guangliang Shan,Hebuli Mu,Lize Pa,Guodong Xu,Ke Wang,Ning Tao,Fen Dong,Shengjiang Ya,Bin Wang

doi:10.3390/ijerph121012792

Abstract

Objective: To estimate the prevalence of diabetes and identify risk factors in the Uyghur and Han population in Xinjiang, China. Methods: A cross-sectional study in urban and rural areas in Xinjiang, including 2863 members of the Uyghur population and 3060 of the Han population aged 20 to 80 years, was conducted from June 2013 to August 2013. Data on fasting plasma glucose (FPG) and personal history of diabetes were used to estimate the prevalence of diabetes. Data on demographic characteristics, lifestyle risk factors, and lipid profiles were collected to identify risks factors using the multivariate logistic regression model. Results: In urban areas, the age- and gender-standardized prevalence of diabetes was 8.21%, and the age- and gender-standardized prevalence of diabetes was higher in the Uyghur population (10.47%) than in the Han population (7.36%). In rural areas, the age- and gender-standardized prevalence of diabetes was 6.08%, and it did not differ significantly between the Uyghur population (5.71%) and the Han population (6.59%). The results of the multivariate logistic regression analysis showed that older age, obesity, high triglycerides (TG), and hypertension were all associated with an increased risk of diabetes in the Uyghur and Han population. Urban residence and low high-density lipoprotein cholesterol (HDL-C) were associated with an increased risk of diabetes in the Uyghur population. Being an ex-drinker was associated with an increased risk of diabetes and heavy physical activity was associated with a decreased risk of diabetes in the Han population. Conclusions: Our study indicates that diabetes is more prevalent in the Uyghur population compared with the Han population in urban areas. Strategies aimed at the prevention of diabetes require ethnic targeting.

Highlights

Diabetes has been rapidly becoming a global public health problem [1]
Compared with the Uyghur population living in rural areas, the Uyghur population living in urban areas were more prevalently male, younger, more likely to have a lower TC, TG, systolic blood pressure (SBP), and diastolic blood pressure (DBP), and were more likely to smoke and drink (p < 0.05)
The Han population living in urban areas had a higher TG, LDL-C, and ratio of TC/HDL-C than the Han population living in rural areas (p < 0.05)

Summary

Introduction

Diabetes has been rapidly becoming a global public health problem [1]. The number of patients with diabetes worldwide was estimated at 382 million in 2014 and is expected to rise to 592 million by the year 2035 [2,3]. In China, the prevalence of diabetes rose from 0.9% [4] in 1980 to 11.6% [5] in. Population aging, economic development, urbanization, and lifestyle changes were likely to lead to the growing epidemic of diabetes [6,7]. Xinjiang is located in the northwest of China, where more than 13 different ethnic groups live. In these groups, the Uyghur and Han populations were the largest, comprising approximately 46% and

Methods

Results

Conclusion