Abstract

BackgroundDepressive symptoms in patients with type 2 diabetes mellitus (T2DM) have attracted much attention in recent years, and negatively affect the health of diabetic patients in numerous ways. This study evaluated the prevalence rate of depressive symptoms in T2DM patients in Shanghai, and the potential factors that may be associated with depressive symptoms in this select population.MethodsA total of 865 T2DM patients were recruited from Longhua Street, Xuhui, Shanghai by simple random sampling, and all the patients were assessed with the Zung Self-rating Depression Scale to screen for depressive symptoms. Factors associated with depressive symptoms were analyzed by logistic regression.ResultsAmong the 865 patients (403 were male, 462 were female, average age 70.13 ± 20.33 years), 304 (35.1%) patients were categorized as having depressive symptoms. Rates of myocardial infarction and stress in one month were higher in the depressive symptoms group than in the non-depressive symptoms group by the X2 test. Rates of patients having a job, having a college education or above, and sleeping less than 7 h/24 h day were also higher in the depressive symptoms group by the X2 test. Body mass index, and levels of total cholesterol, triglyceride, urea, creatinine, uric acid, and homocysteine were higher in the depressive symptoms group by the independent samples t test and non-parametric test. Sleeping hours, history of myocardial infarction, stress in one month, working status, and total cholesterol were significantly associated with depressive symptoms (p < 0.05).ConclusionsIn the Chinese population analyzed in this study, the prevalence rate of depressive symptoms in patients with T2DM was high. Further research on the relationship between diabetes and depressive symptoms is necessary in a wider Chinese population.

Highlights

  • Depressive symptoms in patients with type 2 diabetes mellitus (T2DM) have attracted much attention in recent years, and negatively affect the health of diabetic patients in numerous ways

  • Subjects who met the following inclusion criteria were eligible for participation: (1) diagnosed as T2DM according to World Health Organization criteria in 1999; (2) without mental disease and related family history; (3) no history of drugs that influenced mental health; and (4) individuals who volunteered to participate in this study

  • This study shows for the first time the prevalence of depressive symptoms of T2DM patients in the biggest city in China

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Summary

Introduction

Depressive symptoms in patients with type 2 diabetes mellitus (T2DM) have attracted much attention in recent years, and negatively affect the health of diabetic patients in numerous ways. It was found that people with diabetes are at an increased risk of experiencing depressive conditions in their lifetime. It was noted that effective treatment for depression may greatly attenuate the strong link between depression and mortality in an older population with T2DM [11]. This depression often remains unrecognized and untreated [12], increasing the prevalence of depression among people with T2DM [12,13]. It is critical to diagnose depression in diabetic patients as early as possible and provide them with the corresponding treatments

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