Abstract

Background: In Pakistan, almost 30% population is between 15 to 29 years of age, with university enrollment rates of 10–15%. Although there is a growing concern on mental health of university students across the globe, studies from low and middle income countries such as Pakistan are scarce. We conducted a systematic review and meta-analysis of prevalence of depressive symptoms among Pakistani university students.Methods: PubMed, Web of Science, PsycInfo and Google Scholar were searched between 15 to 30th January 2020. Cross-sectional and longitudinal studies, published till 31st December 2019 were included. Data on study characteristics and prevalence of depressive symptoms were extracted. Meta-analysis was conducted using random effects models. To estimate subgroup difference based on study characteristics, meta-regression and sub-group analyses were conducted.Results: In total, 26 studies involving 7,652 participants were included in review. Overall prevalence of depressive symptoms was 42.66% (95% CI: 34.82% to 50.89%), with significant heterogeneity among studies. Subgroup analyses revealed a significant difference in prevalence estimates based on depression screening instrument and study major. Statistically significant differences were observed among studies employing different psychometric scales (test for subgroup differences, Q = 21.92, p < 0.05) and between students from different study majors (test for subgroup differences, Q = 3.76, p = 0.05).Conclusion: Our study found that overall prevalence of depressive symptoms among university students in Pakistan was 42.66%, however, findings should be interpreted with caution. Large scale epidemiological surveys using valid and reliable tools are needed to better estimate prevalence of depression among Pakistani university students.

Highlights

  • Depressive disorders are leading cause of disability worldwide [1, 2]

  • In this systematic review and meta-analysis of 26 studies involving 7652 university students, prevalence of depressive symptoms was found to be 42.66%

  • We found only 26 studies in four major databases, without publication dates restrictions

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Summary

Introduction

Depressive disorders are leading cause of disability worldwide [1, 2]. Studies suggest that most Common Mental Disorders (CMDs) have their first onset before the age of 24 [3]. Anxiety and mood disorders are highly prevalent among young people aged 18–29 years. Almost 40% of young people experience their first episode of depression before the age of 20, with an average age of onset in the mid-20s [4]. These years are most important for education, employment and social relationships. 24 to 34% university students experience depressive symptoms [5,6,7,8,9]. There is a growing concern on mental health of university students across the globe, studies from low and middle income countries such as Pakistan are scarce. We conducted a systematic review and meta-analysis of prevalence of depressive symptoms among Pakistani university students

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