PREVALENCE OF COMORBIDITIES AND THEIR IMPACT ON MORTALITY IN COVID-19 PATIENTS - A CROSS SECTIONAL STUDY IN A TERTIARY CARE COVID HOSPITAL.

Abstract

Background: Since the origin of novel corona virus (COVID-19) in December 2019, it engulfed more than 200 countries worldwide within short time and was declared as pandemic by WHO. Even though the overall fatality rate is low in COVID-19, presence of certain risk factors and comorbidities more likely result in severe disease and subsequent mortality. Methodology: Retrospectively we evaluated the details of total 200 COVID-19 patients from the medical records. These 200 patients include two groups. Each group consisted of 100 patients. One group consisted 100 patients who were discharged successfully after recovery from COVID-19. Second group consisted 100 patients who demised during hospital stay with COVID-19. We have studied prevalence of comorbidities and their impact on mortality in these two groups in relation to gender, severity. This was a cross sectional study of COVID-19 patients admitted from 01-04-2020 to 31-05-2020 (period of two months) in our state COVID tertiary care hospital, Vijayawada, Andhra Pradesh. Results: There was no statistically significant association between presence of comorbidities and gender in relation to mortality. There was statistically significant association between presence of comorbidities and severity of disease. The association of comorbidities and mortality was statistically significant. Conclusion: Patients with COVID-19 who have comorbidities are more likely to have severe disease course, rapid progression, increased need for admission in ICU and mortality.