Abstract
Background: Lichen Planus is a common mucocutaneous disease with unknown etiology. Immunodeficiency is a known predisposing factor to this disease. Oral Candidiasis which is an opportunistic fungal infection, commonly affects healthy and immune-compromised patients. Candida has different species bearing different treatments. In this study, researchers aimed to detect the frequency and colonization rate of Candida and its association with different factors such as lesion types of oral lichen Planus (OLP).Materials and Methods: Thirty seven untreated oral lichen Planus patients, attending the Clinical Department of Oral Medicine at Shiraz Dental School in 2011, were selected. Swab method and CHROMagar media were used to obtain samples incubated for 48 hours at 30 ºC. Fungal species were detected considering colony color changes.Results: In the culture test, approximately 80% of samples were positive of non-reticular type. About 40% of positive samples were of Candida non-albicans (C.Non-albicans) type. Among C. Non-albicans, 85% were non-reticular type among OLP patients. There was no significant statistical difference in prevalence of Candida albicans (C.albicans) and C. Non-albicans in OLP patients.Conclusion: Based on results, certain biotypes of Candida were not confirmed responsible for OLP patterns.[GMJ.2014;3(4):252-5]
Highlights
Lichen Planus is a common chronic inflammatory disease of unknown etiology which usually affects oral mucosa with a variety of clinical patterns including reticular, papular, plaque-like keratoses, atrophic sur- GMJCandida Species in Oral Lichen Planus Patients disease [6,7,8]
Considering the fact that various species of Candida respond differently to treatment and patients with oral lichen Planus (OLP) may be infected by a variety of Candida species, this study was aimed at evaluating the prevalence of oral Candidiasis, the species distribution in OLP patients and their association with different factors such as patterns of OLP lesions
Among Candida species, both C.albicans and C.dubliniensiscan can produce germ tubes [16]; in order to confirm the results with germ tube method, specimens of the yeast colony were added to a 0.5 ml test tube containing human serum which was kept in 37 oC steam bath for 1.5-2 hours
Summary
Lichen Planus is a common chronic inflammatory disease of unknown etiology which usually affects oral mucosa with a variety of clinical patterns including reticular, papular, plaque-like keratoses, atrophic sur- GMJCandida Species in Oral Lichen Planus Patients disease [6,7,8]. Considering the fact that various species of Candida respond differently to treatment and patients with OLP may be infected by a variety of Candida species, this study was aimed at evaluating the prevalence of oral Candidiasis, the species distribution in OLP patients and their association with different factors such as patterns of OLP lesions. Researchers aimed to detect the frequency and colonization rate of Candida and its association with different factors such as lesion types of oral lichen Planus (OLP).Materials and Methods: Thirty seven untreated oral lichen Planus patients, attending the Clinical Department of Oral Medicine at Shiraz Dental School in 2011, were selected. Fungal species were detected considering colony color changes.Results: In the culture test, approximately 80% of samples were positive of non-reticular type. Non-albicans in OLP patients.Conclusion: Based on results, certain biotypes of Candida were not confirmed responsible for OLP patterns.[GMJ.2014;3(4):252-5]
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