Abstract
BackgroundChronic complications are the major outcome of type 2 diabetes mellitus progress, which reduce the quality of life of patients, incur heavy burdens to the health care system, and increase diabetic mortality. The aims of this study were to describe the prevalence of chronic complications among urban Chinese type 2 diabetic outpatients; and to analyze the associations between chronic complications and patients' demographics, diabetic related clinical characteristics.MethodsThis cross-sectional hospital-based study was carried out in 4 major Chinese cities: - Shanghai, Chengdu, Beijing and Guangzhou. The survey was conducted from March to July in 2007 among 1,524 type 2 diabetic outpatients. The subjects were interviewed face-to-face by trained interviewers using a questionnaire to capture information on demographics, disease presentations and complications. All the subjects were invited to have a HbA1c test free of charge by the standardized method with Bio-Rad Variant II.ResultsOf the 1,524 study subjects, 637 (41.8%) were male, and the mean age was 63.3 ± 10.2 years. At least one chronic complication was diagnosed in 792 individuals (52.0%) of the study subjects; 509 (33.4%) presented with macrovascular complications and 528 (34.7%) with microvascular complications. The prevalence of cardiovascular and cerebrovascular conditions, neuropathy, nephropathy, ocular lesions and foot disease were 30.1%, 6.8%, 17.8%, 10.7%, 14.8% and 0.8%, respectively. The prevalence of chronic complications varied between cities, and significantly increased with age and duration of diagnosed diabetes. The mean of HbA1c in diabetic patients with chronic complications was 8.2% ± 1.6% and 63.0% of the subjects with type 2 diabetes related complications had a poor glycemic control with the HbA1c > 7.5%.ConclusionsChronic complications are highly prevalent among type 2 diabetic outpatients, the glycemic control of diabetic patients with chronic complications was poor, and future efforts should be directed at intensive blood glucose control, strengthening early diagnosis and improving case management to prevent and minimize the occurrence of complications.
Highlights
Type 2 diabetes mellitus (T2DM) has become one of the most important chronic public health problems[1]
It is well known that chronic complications are the major outcome of type 2 diabetes mellitus (T2DM) progress, which reduce the quality of life of patients, incur heavy burdens to the health care system, and increase diabetic mortality [10-12]
The inclusion criteria were: (1) T2DM diagnosed in accordance with international standards (WHO 1999), i.e. fasting plasma glucose (FPG) ≥ 7.0 mmol/L and/or 2 hours postprandial plasma glucose (PPG) or casual plasma glucose ≥ 11.1 mmol/L[17]; (2) under regular anti-diabetic drug treatment for at least 1 year; (3) ≥ 18 years old; (4) resident in the respective city for ≥ 2 years; (5) provided written informed consent to participate in the study
Summary
Type 2 diabetes mellitus (T2DM) has become one of the most important chronic public health problems[1]. T2DM is a growing cause of disability and premature death, mainly through cardiovascular disease and other chronic complications[1-3]. Data from prospective and cross-sectional studies consistently point to the fact that diabetic patients are more likely to develop micro- as well as macro-vascular conditions[7-9]. It is well known that chronic complications are the major outcome of T2DM progress, which reduce the quality of life of patients, incur heavy burdens to the health care system, and increase diabetic mortality [10-12]. Chronic complications are the major outcome of type 2 diabetes mellitus progress, which reduce the quality of life of patients, incur heavy burdens to the health care system, and increase diabetic mortality. The aims of this study were to describe the prevalence of chronic complications among urban Chinese type 2 diabetic outpatients; and to analyze the associations between chronic complications and patients' demographics, diabetic related clinical characteristics
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
