Abstract
to establish the prevalence of salvage of central venous catheters in newborns with bloodstream infection caused by coagulase-negative staphylococci. retrospective cross-sectional study with 136 newborns admitted to the Neonatal Intensive Care Unit between 2011 and 2017. The total of 143 infection events undergoing antibiotic therapy were evaluated. among the 143 infection events, 39 catheters in which antibiotic therapy was used were saved and in 69 cases, the device was removed. Positive central blood culture and single lumen catheter were factors associated with salvage failure. The probability of salvage decreased with infections diagnosed from 15 days of using the catheter. Negative blood culture raised the chance of salvage by fourfold. the use of antibiotic therapy in the treatment of infections resulted in a low prevalence of salvage of the central venous catheter. The probability of salvage was associated with variables of the device.
Highlights
METHODSNeonatal care procedures in intensive care units (ICUs) require the use of advanced technology and the central venous catheter (CVC) is one of the most common invasive procedures used in these patients[1]
Phlebotomy consists of dissection, isolation, catheterization and ligation of the distal vein in most cases, it is indicated in emergencies, when peripheral venous access cannot be obtained promptly[8]
In the Multivariate Logistic Regression model, the catheter salvage was considered as a dependent variable, while gestational age (GA), birth weight, sex, length of hospital stay, use of TPN, previous invasive procedures, CVC type and caliber, insertion location, number of lumens, time of catheterization, antibiotic therapy and the positivity of the central blood culture were considered as independent variables
Summary
METHODSNeonatal care procedures in intensive care units (ICUs) require the use of advanced technology and the central venous catheter (CVC) is one of the most common invasive procedures used in these patients[1]. We highlight the umbilical catheterization, the peripherally inserted central venous catheter (PICC) and phlebotomy[2].Together, these three types of catheterization are known as CVC[3]. Vascular access through these devices is crucial for the survival of newborns (NB), providing safe intravenous therapy[4,5]. The PICC is an intravenous device inserted through a superficial or deep vein of the extremity that progresses to the distal third of the superior vena cava. Phlebotomy consists of dissection, isolation, catheterization and ligation of the distal vein in most cases, it is indicated in emergencies, when peripheral venous access cannot be obtained promptly[8]
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