Abstract

Medial arterial calcification (MAC) typically affects the distal vasculature, probably because of a causative relationship with peripheral and autonomic neuropathies. The complex processes involved have recently been reviewed (1). Classic surveys reported that MAC was particularly common in Charcot disease (2,3), suggesting that it might be a specific feature of the condition. However, it is equally possible that it may represent a less specific response to local inflammation. The aim of the present study was to determine the prevalence of MAC in patients with Charcot disease as well as other disorders of the foot such as osteomyelitis and uncomplicated foot ulcers. Cases were identified from a clinic database, for which ethical approval is not …

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