Abstract
Objective: to determine the seroprevalence of Brucella spp in humans.Method: this is an observational study, developed with 455 individuals between 18 and 64 years old, who use the Estratégia de Saúde da Família (Brazil's family health strategy). The serum samples of volunteers underwent buffered acid antigen tests, such as screening, agar gel immunodiffusion and slow seroagglutination test in tubes and 2-Mercaptoethanol. Results: among the samples, 1.98% has responded to buffered-acid antigen, 2.85% to agar gel immunodiffusion test and 1.54% to the slow seroagglutination tests on tubes/2-Mercaptoethanol. The prevalence of Brucella spp was 4.4%, represented by the last two tests. Conclusion: the results of this research suggest that the studied population is exposed to Brucella spp infection.
Highlights
By being able to affect animal and humans, it is considered an anthropozoonosis, because its etiologic agent – which lives in some animals – is transferable to the human species, and it is considered one of the most important health disorders spread worldwide, according to the Food and Agriculture Organization (FAO), the World Health Organization (WHO) and the World Organization for Animal Health (OIE)(6-7)
Due to the severity of the disease and the lack of epidemiological data on the situation of human brucellosis in the State and municipality, this research aimed at determining the seroprevalence of Brucella spp in the human population in the municipality of Marechal Deodoro, Alagoas, Brazil
Our research is an observational study whose objective was to determine the seroprevalence of Brucella spp in the human population in the municipality of Marechal Deodoro, Alagoas, Brazil, estimated population of 45,977 inhabitants
Summary
It is an infection-contagious disease caused by the bacteria of the genus Brucella, spread worldwide, with chronic evolution, showing diffuse granulomatous appearance and characterized by infection of cells of the mononuclear Phagocytic system, caused by facultative intracellular bacteria[1]. In Brazil, in the 1970s, the Ministry of Agriculture, Livestock and Food Supply estimated a loss of US$ 32 million caused by bovine or bubaline brucellosis, only considering animal abortions and the decrease in milk production[6]. In humans it may have acute and latent forms. A common symptom is asthenia and fatigue, accompanied by malaise, cephalalgia, weakness, profuse perspiration with characteristic smell, chills, arthralgia, depression, weight loss, as well as reproductive disorders such as orchitis and erectile dysfunction in men, and abortions and infertility in women, and may be asymptomatic or develop into the chronic form, in addition to osteoarticular complications, bacterial endocarditis and even suppuration of organs such as the spleen and the liver[8,9]
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