Prevalence of Atherogenic Profile and Heart Failure in Vascular Dementia

Abstract

Objectives Purpose of our study was to evaluate the incidence of atherogenic profile, heart failure (HF) and if there is any correlation between these and cognitive impairment (CI) in patients with vascular dementia (VaD). Method This was a retrospective study. We analyzed 35 patients with VaD and 25 age- and sex-matched healthy controls. NINDS-AIREN criteria and Hachinski's ischemic scale were used to identify VaD. Mini Mental State Examination was used to classify CI into mild, moderate and severe. Clinical and biochemical features were investigated by means of standardized tests. Echocardiography was done for evaluate ejection fraction (EF). Results Prevalence of atherogenic profile was increased in VaD compared with controls (72.2% vs 20%, p Conclusions The prevalence of atherogenic profile and heart failure were significantly higher in VaD and were correlated with cognitive impairment.