Abstract

Helicobacter pylori is a bacteria found in many untreated water sources in developing countries. They colonize the luminal surface of gastric epithelium in about 50% of population. Though most infections are asymptomatic, they are the major microorganism causing duodenogastric ulcers, carcinoma of the gastric region and gastric mucosa associated lymphoid tissue (MALT) lymphoma. The serologic study to detect prevalence of Helicobacter pylori was done on healthy blood donors. The cross sectional study was done in a medical college hospital in the state of Kerala; India. The sample was collected from the donated blood. The serum was subjected to serological studies to detect Helicobacter pylori specific IgM and IgG antibodies. The results were noteworthy. A seroprevalence of 29.29% to Helicobacter pylori antibodies was detected in the study group. This is less than similar seroprevalence studies done in different parts of the world. Keywords: Helicobacter pylori, Seroprevalence, Blood donors, Asymptomatic.

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