Prevalence of antibiotic resistance in Enterobacteriaceae among the patients hospitalized in Al-Zahra hospital, Isfahan, Iran

Abstract

Introduction: Enterobacteriaceae are a high prevalent gram-negative species worldwide, which play a major role in various infections. Objectives: The present study aims to assess the prevalence of antimicrobial resistance in Enterobacteriaceae at a tertiary hospital in Isfahan, Iran. Materials and Methods: This cross-sectional laboratory-based study was performed during 2020 in Al-Zahra hospital, Isfahan, Iran. The isolates of all of the clinical samples submitted for the bacterial culture containing Enterobacteriaceae strains were checked for antibiotic resistance during March 2018 to March 2019. Results: The results revealed that the specimens obtained from intensive care units (ICUs) exhibited more resistance than the others. Additionally, the highest abundant antibiotic resistance among inpatients was related to ampicillin/sulbactam, and carbapenem resistance was significantly high. Conclusion: The high prevalence of antibiotic resistance indicated the inappropriate antibiotic prescription in this center. The results emphasized the importance of preventive strategies and restrictions in over-the-counter antibiotic consumption.