Prevalence in clinical characteristics and oral anticoagulation therapy for patients with atrial fibrillation in different inpatient departments

Abstract

Objective To investigate the status of oral anticoagulation therapy for patients with atrial fibrillation (AF) in different inpatient departments, and to analyze the main factors affecting the rate of anticoagulant therapy. Methods A total of 533 patients with non-valvular atrial fibrillation (AF) who hospitalized in Beijing Tsinghua Changgung Hospital in 2017 were enrolled. The clinical characteristics, CHA2DS2-VASc embolization risk score and HAS-BLED bleeding risk score were recorded. SPSS 22.0 software was used for statistical analysis. Results Among 533 individuals enrolled, 491 (92.1%) had a CHA2DS2-VASc≥2. Oral anticoagulants (OACs) were prescribed in 42.0% patients. The patients registered in Cardiology Department had significantly higher anticoagulation therapy rate than the patients registered in Neurology Department, Surgical and other Internal Medicine Departments (54.0% vs. 39.7% vs. 37.3% and 24.6%, P 3(OR: 0.316, 95%CI: 0.129-0.775, P=0.007) and combined with chronic renal dysfunction (OR: 0.516, 95%CI: 0.285-0.936, P=0.010) were predictors of non-anticoagulation therapy. Conclusions The use of OACs therapy in AF patients is still low in real world. The predictors still include whether it is persistent AF and which department the patients registered. Improving physician's anticoagulation awareness might be a solution to increasing anticoagulation trend in patients with AF. Key words: Atrial fibrillation; Anticoagulation therapy; New oral anticoagulants