Abstract
The journal is the official publication of the College of Surgeons of Sri Lanka. Its mission is to reach the highest standard of scientific surgical practice by dissemination of high quality scientific information and to foster and promote the growth of scientific surgery in Sri Lanka and in the region. The Sri Lanka Journal of Surgery publishes peer-reviewed leading articles, review articles, scientific articles, perspectives and case reports in the field of surgery and broadly related surgical sciences The journal adheres to the publication ethics as portrayed by the Committee on Publication Ethics (COPE) and is a member of this organisation. It is listed as an ICMJE journal which follow its recommendations (ICMJE recommendations) on Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals.
Highlights
Metabolic syndrome independently has a significant alliance with both non-alcoholic fatty liver disease (NAFLD) and gall stone disease (GSD)
Body mass index > 25kg/m2 and central abdominal obesity was a strong predictor of steatosis in GSD with NAFLD (p 0.041, 0.029 respectively)
Central abdominal obesity and low levels of high-density lipoprotein were a strong predictor of fibrosis in NAFLD (p 0.040, 0.037 respectively)
Summary
Metabolic syndrome independently has a significant alliance with both non-alcoholic fatty liver disease (NAFLD) and gall stone disease (GSD). NAFLD can present variably in different individuals from simple steatosis to non-alcoholic steatohepatitis (NASH). Factors which are found responsible for gallstone formation are: female gender, obesity, hypertriglyceridemia, diabetes mellitus, insulin resistance and metabolic syndrome (MS) [2]. Non Alcoholic Fatty Liver Disease (NAFLD) has become the most common liver disease the world over and is considered as the hepatic manifestation of MS. Diabetes, insulin resistance, hypertension and other metabolic risk factors is increasing among Indians. Asian-Indians are more at risk to have NAFLD because of a higher incidence of insulin resistance even at lower BMI [7]. The prevalence of NAFLD among physically active but economically deprived rural adults of Sri Lanka is 18% which strengthens the existing evidence that Asians have a susceptibility of visceral fat accumulation [8]
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