Abstract
BackgroundTo describe the prevalence and associations of posterior vitreous detachment (PVD) in a rural adult Chinese population.MethodsAll eligible subjects were requested to carry out a comprehensive eye examination; PVD was a pre-specified outcome variable and was determined via biomicroscopical examination (slit-lamp biomicroscopy) with a +90-D preset lens after mydriasis. Prevalence was standardized to China population census (2000).Results5890 (86.2%) subjects completed the examination of slit-lamp biomicroscopy with a +90-D lens. PVD was present in 160 participants (2.7%); the standardized prevalence was 2.0% (95% confidence interval [CI], 1.6-2.3%). PVD developed increasingly with age (P for trend < 0.001) for both men and women. Using a multivariate regression model, older people were found to run a higher risk of developing PVD than younger people, and women were found to have a higher risk than men (OR, 2.9; 95% CI, 1.5-5.9). Diabetes, hypertension, smoking, drinking, and intraocular pressure (IOP) were not significantly associated with PVD.ConclusionsAbout one in fifty people is found to have PVD in this population-based study. Age and female are independently associated with PVD occurrence.
Highlights
To describe the prevalence and associations of posterior vitreous detachment (PVD) in a rural adult Chinese population
Of the 6830 participants, 5890 (86.2%) completed the examination of slit-lamp biomicroscopy with a +90-D preset lens in the county hospital. 807 (11.8%) at temporary study sites in the villages and 114 (1.7%) at home completed the preset lens examination without mydriasis, which might have made it impossible to detect PVD, and, we excluded these participants from the calculation of prevalence
Prevalence of PVD PVD was present in 160 participants (2.7%)
Summary
To describe the prevalence and associations of posterior vitreous detachment (PVD) in a rural adult Chinese population. Losing its gel-like consistency with aging, the vitreous body may eventually detach from the retina and optic disc, clinically described as posterior detachment of the vitreous body (PVD) [1]. PVD is related to the pathogenesis of retinal tears, subsequent retinal detachment, and some other ocular diseases such as macular holes and vitreous or retinal hemorrhages [2,3,4,5]. Information on the prevalence of PVD is largely lacking. Have been studied with respect to the development of PVD. We described the prevalence and associations of PVD in a large sample of Chinese population aged 30+ years, living in Handan, Hebei Province, China
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