Abstract

BackgroundNocturnal enuresis (NE) has a negative impact on children’s health and imposes a long-term burden on families. With economic development and cultural improvements, parents and medical professionals pay more attention to NE. The aim of this study was to investigate the prevalence and risk factors of NE among children ages 5–12 years in Xi’an, China.MethodsA stratified cluster sampling method was used to conduct a cross-sectional study of NE in 10 kindergartens and 20 primary schools in Xi’an. We used univariate analysis to compare the prevalences of characteristics such as gender, duration of disposable diaper (DD) use, toilet training onset time, daily living habits, academic performance, and family history of NE. Logistic regression analysis was used to calculate odds ratio and to determine risk factors of NE.ResultsThe study included 6568 children ages 5–12 years, of which 262 (3.99%) had NE. The prevalence rates of NE decreased with age, with the highest prevalence at age 5 (9.09% for boys; 6.03% for girls). However, the prevalence increased with duration of DD use. Children experienced more NE if they never accepted toilet training (7.83%) or if they drank sugary beverages during the day (5.36%). Sleep disorders, sweets intake, drinking low amounts of plain water during the day, and family history of NE, were statistically associated with NE.ConclusionNE was closely associated with a family history of NE, being male, long-term use of DD, delayed toilet training, drinking sugary beverages and/or consuming little plain water, and sleep disorders. A supportive parental attitude towards NE and timely medical treatment can improve the quality of life of enuretic children.

Highlights

  • Nocturnal enuresis (NE) has a negative impact on children’s health and imposes a long-term burden on families

  • The prevalence of NE in 5-year-old children was higher than the prevalence at older ages (9.09% for boys; 6.03% for girls)

  • We found that the occurrence of NE in children with a family history of NE was significantly higher than that in the general population

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Summary

Introduction

Nocturnal enuresis (NE) has a negative impact on children’s health and imposes a long-term burden on families. With economic development and cultural improvements, parents and medical professionals pay more attention to NE. The aim of this study was to investigate the prevalence and risk factors of NE among children ages 5–12 years in Xi’an, China. Childhood nocturnal enuresis (NE) refers to the symptoms of intermittent urinary incontinence during sleep, at a minimum age of 5 years, with a minimum duration of three months, and a minimum of one episode per month [1]. Contributing elements include family history of NE, changes in antidiuretic hormone secretion rhythm, sleep disorders, retarded bladder maturity, immature nerve development, psychology, and environment [2,3,4]. In China, NE prevalence was found to vary by region, ranging from 4.07 to 10.3% [9, 10], and NE occurred more frequently with boys [3, 11]

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