Prevalence and risk factors of microalbuminuria in patient with diabetic mellitus at northern part referral hospital in Thailand

Abstract

Objective To identify prevalence of microalbuminuria and its associated risk factors including old age, hypertension, dyslipidemia, diabetic retinopathy and metabolic syndrome in diabetic patients in Lampang, Thailand. Material and method 2231 diabetic patients at Lampang Hospital were recruited in this cross-sectional study. Eye examination, blood pressure and abdominal circumference measurements were done. Blood was collected and checked for glucose, cholesterol, and renal function. Single-spot morning urine was collected for urine albumin–creatinine ratio (UACR). UACR 30–300 mg/g indicated microalbuminuria (by National Kidney Foundation). Multivariate logistic regression method including odds ratio and 95% confidence interval were used to analyze the data. Results Microalbuminuria was found in 27% of the patients. There were clear association between creatinine clearance and microalbuminuria. Older age for every 10 years and diabetic retinopathy had relationship with microalbuminuria in overall and female patients while had no statistically significant in male patients. Conclusion Microalbuminuria is common in Thai diabetic patients. Older age and history of diabetic retinopathy increase the risk of microalbuminuria in overall and female patients. Screening for albuminuria should be done in every diabetic patient for early prevention of diabetic nephropathy.