Abstract
This cross-sectional study aimed to determine the prevalence of Helicobacter pylori infection and its association with tobacco consumption (smoking and snuff use) in Peshawar, Pakistan. 150 blood samples were collected from H. pylori suspected patients in tertiary care hospitals. Demographic data, tobacco consumption habits, and potential risk factors were gathered through a questionnaire. The prevalence of H. pylori among smokers and snuff users was 42%. All participants had a history of tobacco use, with 59% being smokers and 41% being snuff users. Most participants (81%) had not been tested for H. pylori before. Eight risk factors associated with H. pylori infection were investigated, including family history, stomach ulcers or gastritis, consumption of spicy or heavily seasoned food, poor hygiene practices, low socioeconomic status, history of antibiotic use, close contact with infected individuals, and consumption of contaminated food or water. Participants' opinions and beliefs about these risk factors varied. The study demonstrated significant associations between H. pylori antigen detection and smoking, snuff use, overcrowding, and various risk factors such as family history, dietary habits, hygiene practices, socioeconomic status, antibiotic use and exposure to contaminated water or food. The study emphasizes the need for further research to understand these risk factors and their impact on H. pylori infection.
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