Abstract
The incidence of colorectal polyps is rising. Certain types of polyps are considered to be the precursor lesions for colorectal cancers. To investigate the prevalence and related factors of colorectal polyps in Chinese subjects, we first performed a cross-sectional study. A total of 3066 subjects were documented, and the prevalence of colorectal polyps was 18.1%. Then we evaluated the incidence and risk factors of polyps via a retrospective cohort study in the same population. 561 subjects who received at least twice surveillance colonoscopies with available reports during the study period and had no polyp at the first endoscopy were included in the retrospective cohort study, of whom 19.1% developed colorectal polyps. Regular smoking was independently associated with the presence and development of colorectal polyps. Further analyses indicated that polyps were associated with smoking status, daily cigarette consumption, and drinking habit. Moreover, smoking tends to be more relavent to rectal, small and single polyp. In conclusion, colorectal polyp is a common disease in China. Exploring the epidemiology and risk factors may improve the prevention of colorectal polyps, even colorectal cancer.
Highlights
The incidence of colorectal polyps is rising
As for Colorectal cancer (CRC), a population-based colorectal cancer screening program in China suggested that age, gender, BMI, family history, meat intake and smoking were associated with colorectal neoplasms[11]
The results indicated that older age, male, regular smoking, higher total cholesterol (TC) and white blood cell (WBC) count were significantly associated with the presence of colorectal polyps
Summary
The incidence of colorectal polyps is rising. Certain types of polyps are considered to be the precursor lesions for colorectal cancers. To investigate the prevalence and related factors of colorectal polyps in Chinese subjects, we first performed a cross-sectional study. We evaluated the incidence and risk factors of polyps via a retrospective cohort study in the same population. Population characteristics, living habits, and health conditions are closely related to the presence and development of colorectal polyps and cancers. Most evidence came from case-control or cross-sectional studies, and there is still no cohort study to evaluate the risk factors for colorectal polyps in China. We first evaluated the prevalence of colorectal polyps and factors associated with the presence of this disease in a cross-sectional study. We investigated the incidence and risk factors for the colorectal polyps via a retrospective cohort study. Associations between the risk factors and features of colorectal polyps were further assessed
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