'Prevalence and Risk Factors Associated with Posterior Bleeding of Esophageal Varcies in Patients With Liver Cirrhosis'

Abstract

Introduction: Rebleeding of esophageal varices is a serious complication, showing a high risk for the patient who suffers from it, since it significantly increases morbidity and mortality. It was set as an objective to determine the prevalence and factors associated with rebleeding after ligation of esophageal varices in patients with liver cirrhosis, admitted to the Hospitalization Service of the Jose Carrasco Arteaga Hospital during the period January 2013 to December 2017. Materials and Methods: Observational, analytical, cross-sectional study. 179 patients who met the inclusion criteria participated. The data were analyzed using the SPSS version 15 program. For the association analysis, the chi 2 test was applied, obtaining a prevalence ratio, with 95% CI and p value, the information was presented by means of personalized tables. Results: The prevalence of rebleeding was 49.2% (95% CI 41.55% - 56.76%), being more frequent in older men≥ 65 years with 64.8%. The79.3% of patients presented postoperative complications, where neurological alteration corresponded to 49.2% and 43% died after the procedure. There was a statistical relationship with factors such as: TPT greater than 33.3 (PR: 1.91, 95% CI 1.07 -3.39, P value = 0.00); moderate, severe anemia (PR: 1.43, 95% CI 1.05 - 1.96, P value = 0.02) and blood transfusion (PR: 2.23, 95% CI 1.37 - 3.65, P value = 0.00). Conclusions: The prevalence of rebleeding was high, finding an association with: partial thromboplastin time, moderate and severe anemia, and having received blood transfusions upon admission. Funding Statement: Self financed. Declaration of Interests: The authors have no conflict of interest. Ethics Approval Statement: Authorizations obtained from both the bioethics committee of the Universidad Catolica de Cuenca and the Jose Carrasco Arteaga Hospital.