Prevalence and Pattern of Dyslipidemia among Patients Attending in a Tertiary Care Hospital in Bangladesh

Abstract

Background: Dyslipidemia was defined according to the third report of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III, USA, 2001), TC level ≥200 mg/dl, HDL-C level <40 mg/dl, LDL-C level ≥130 mg/dl, TG ≥150 mg/dl. Dyslipidemia was defined as having at least one of the following: high TC, high LDL- C, low HDL-C and high TG. Dyslipidemia is considered as a major risk factor for several life-threatening diseases. Aim of the study: The aim of this study was to assess the prevalence and pattern of dyslipidemia among patients attending in a tertiary care hospital in Bangladesh. Methods: This cross-sectional analytical study was conducted at the Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. The study duration was one year from March 2016 to February 2017. Non-probability sampling method was used in study subject selection. In total 510 patients underwent lipid profile analysis as the diagnostic procedure of several diseases was finalized as the study population. Fasting blood samples were collected from study subjects to estimate the serum TC, TG, and HDL-C. LDL cholesterol was calculated using the Friedewald equation [LDL-C= (TC—HDL-C)—(TG/5)]. Collected data was checked, edited and then processed with the help of the software Statistical Package for Social Sciences (SPSS) version 23 program. Results: In this study, among total 510 participants 245 were with dyslipidemia and the rest 265 were with normo-lipidemia. So, prevalence of dyslipidemia was found as 48% among total patients. As per the distribution of study subjects according to lipid disorder pattern we observed that, 19.4%, 15.3% and 13.3% of our dyslipidemia patients were with isolated hypercholesterolemia, isolated hypertriglyceridemia and mixed hyperlipidemia respectively. In assessing the pattern of dyslipidemia according to age in considering mean levels of isolated hypercholesterolemia, ........