Abstract
We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission. Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
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