Prevalence and Molecular Characterization ofCyclospora cayetanensis, Henan, China

Yang Zhou,Xiaoshan Zhang,Changshen Ning,Lihua Xiao,Kanda Fu,Biao Lv,Jinfeng Zhao,Huixia Yao,Yanru Sun,Michael J Arrowood,Yaqiang Wang,Rongjun Wang,Ke Shi,Qiang Wang,Meng Qi,Fuchun Jian,Longxian Zhang

doi:10.3201/eid1710.101296

Abstract

To determine prevalence of Cyclospora cayetanensis infection in Henan, China, we conducted a study of 11,554 hospital patients. Prevalence was 0.70% (95% confidence interval 0.70% ± 0.15%), with all age groups infected. Most cases were found in the summer. Minor sequence polymorphisms were observed in the 18S rRNA gene of 35 isolates characterized.

Highlights

To determine prevalence of Cyclospora cayetanensis infection in Henan, China, we conducted a study of 11,554 hospital patients
The overall infection rate of C. cayetanensis was similar between Zhengzhou and Kaifeng: 0.60% versus 0.79% (Pearson correlation >0.05; Table 1)
The overall infection rate of 0.70%. In this 23-month investigation in 2 Henan Province cities is similar to data previously obtained in an urban area in the neighboring Anhui Province (0.92%, 95% CI ± 1.04%) [6] and studies in Albania (0.63%, 95% CI ± 0.55%) [7] and Tanzania (0.91, 95% CI ± 1.25%) [8] but higher than the infection rate in the United Kingdom (0.07%, 95% CI ± 0.07%) [9]

Summary

Introduction

To determine prevalence of Cyclospora cayetanensis infection in Henan, China, we conducted a study of 11,554 hospital patients. Cyclospora oocysts were detected in 81 (0.70%; 95% confidence interval [CI] 0.70% ± 0.15%) of 11,554 patients by microscopy (Table 1). Cyclospora oocysts were seen in samples from patients in all age groups, the age group 7–17 years had the highest detection rate (1.47%, 95% CI ± 0.91%; Pearson correlation >0.05) (Table 1).

Results

Conclusion