Abstract
Abstract Objectives: to estimate the prevalence and the factors associated with the colonization by group B streptococcus (GBS) in pregnant women from the urban area attended at health units in a municipality in northeastern Brazil. Methods: it is a cross-sectional study conducted from January 2017 to March 2018. Vagino-rectal swabs were collected from 210 pregnant women between 32 and 40 weeks of gestation. The swabs were seeded on 5% sheep blood agar and on chromogenic agar. For confirmatory identification of GBS, the CAMP test and latex agglutination were used. Descriptive analysis and univariate and multivariate association analysis were performed using a multinomial logistic model. Results: the prevalence of GBS colonization among pregnant women was 18.1% (n = 38), and a statistically significant association (p<0.05) was found for income and parity variables in the group of older women in the univariate analysis, and for skin color, age and parity in the final multivariate analysis. Conclusions: the prevalence of maternal colonization by GBS was similar to that described in other studies. Although some risk factors, such as skin color, age and parity, were associated with colonization, other studies are essential to establish more information on pregnant women more likely to be colonized by GBS.
Highlights
The Group B Streptococcus (GBS) or Streptococcus agalactiae is part of the mucous membrane microbiota of humans and animals, mainly colonizing the intestinal and genitourinary tracts.[1]In pregnant women, GBS is associated with infections such as cystitis, pyelonephritis and endometritis
Pregnant women undergoing prenatal care at the health unit with a gestational age of 32 to 40 weeks who agreed to participate after applying the Informed Consent Form (ICF) were considered eligible to participate in the study
The 18,1% prevalence of maternal colonization by GBS agrees with most national surveys.[8,12,15,16]
Summary
The Group B Streptococcus (GBS) or Streptococcus agalactiae is part of the mucous membrane microbiota of humans and animals, mainly colonizing the intestinal and genitourinary tracts.[1]. GBS is associated with infections such as cystitis, pyelonephritis and endometritis. It may be related to impairment in the evolution of pregnancy, with possible occurrence of abortion, intrauterine fetal death, chorioamnionitis and early rupture of the membrane and premature delivery.[2]. GBS is the main etiological agent associated with early-onset neonatal sepsis. Among newborns of parturients colonized by GBS, 1-2% will develop invasive disease of early onset.[3,4] These exposed newborns can develop serious illnesses, such as pneumonia, sepsis and meningitis.[5]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
