Abstract
BackgroundPerinatal depression is a significant contributor to maternal morbidity and mortality globally. Migrant women, particularly those living in low- and middle-income settings, represent a particularly vulnerable group due to stressors experienced before, during and after migration. The vast majority of global migration flows occurring within and between low- and middle-income regions, yet existing evidence focuses predominantly on migrants in high-income destinations. This study aimed to redress this significant gap in the evidence by determining the prevalence and determinants of perinatal depression among migrant women on the Thai-Myanmar border.MethodsA cohort of labour migrant and refugee women was followed-up from the first trimester of pregnancy to one month post-partum. Depression status was assessed in the first, second and third trimesters of pregnancy and at one month post-partum using the Structured Clinical Interview for the Diagnosis of DSM-IV Disorders. Women diagnosed with depression had immediate access to care. Data on potential demographic, social and clinical associated factors was collected using a questionnaire. Prevalence and incidence of any depressive disorder and moderate-severe depressive disorder was calculated. Univariable and multivariable logistic regression using complete case analysis was used to estimate odds ratios (OR) of association between exposure variables and depression status.ResultsFive hundred sixty-eight women participated. Period prevalence (from first trimester of pregnancy to one month post-partum) of moderate-severe perinatal depression was 18.5% (95% CI 15.4–21.9%). Overall, 15.4% (95% CI 11.8–19.6%) of women developed new-onset moderate-severe depression during the study period. Forty-two participants received treatment for depression. Risk factors were interpersonal violence (OR 4.5; 95% CI 1.9–11.1); history of trauma (OR 2.4; 95% CI 1.4–4.3); self-reported history of depression (OR 2.3; 95% CI 1.2–4.2); labour migrant status (OR 2.1; 95% CI 1.1–4.0); low social support (OR 2.1; 95% CI 1.1–3.7); and maternal age (OR 1.1 per year; 95% CI 1.0–1.1). Limitations of the study include that culturally specific manifestations of depression may have been missed.ConclusionsPerinatal depression represents a significant burden among migrant women on the Thai-Myanmar border. Programmes to address the determinants along with early case identification and effective treatment and referral systems are key to addressing perinatal depression in this low-resource setting.
Highlights
Perinatal depression is a significant contributor to maternal morbidity and mortality globally
Risk factors were interpersonal violence; history of trauma; self-reported history of depression; labour migrant status; low social support; and maternal age
Perinatal depression represents a significant burden among migrant women on the Thai-Myanmar border
Summary
Perinatal depression is a significant contributor to maternal morbidity and mortality globally. Migrant women, those living in low- and middle-income settings, represent a vulnerable group due to stressors experienced before, during and after migration. Untreated perinatal depression has been associated with a number of significant adverse outcomes including negative health behaviours in pregnancy [1], subsequent chronic and recurrent depression [1, 2], impaired ability to work and provide care, relationship breakdown [2, 5] and suicide – an important contributor to maternal deaths globally [6, 7]. Migrant women constitute a particular risk group, experiencing many of the risk factors for perinatal depression prior to, during and following displacement [8,9,10]. Forced displacement is often associated with particular challenges, even planned migration can cause significant distress through separation from families and friends, isolation, lack of host language proficiency, discrimination and violence [10,11,12]
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