Prevalence and Determinant Factors of Chronic Calculous Cholecystitis among Senile Population Arar, KSA

Abstract

Background: chronic calculous cholecystitis is an inflammatory disease which affects the gallbladder wall and causes motoric-tonic dysfunctions of the biliary system accompanied by gallstones in the lumen of the gallbladder and biliary pain. Among aging study groups, the prevalence of gallstone disease is likely to increase. Aim of the Work: to determine the prevalence and determinant factors of chronic calculous cholecystitis among senile population in Arar, KSA. Patients and Methods: the present cross sectional community based study was conducted in Arar city, Northern Border Province, KSA on 217 adult people aged 50 years and more. Data were collected through personal interviews with the study population and filling the questionnaire which guided us to the data of socio-demographic status, smoking, chronic diseases, already previously diagnosed with chronic calculous cholecystitis, after ensuring the diagnosis by reviewing the accompanied health reports and/or prescriptions and asking the accompanied caregivers about the case. Results: the mean age of the participants (± SD) was 69.9 (±9.3) years; male to female ratio was 43.8 to 56.2. The overall prevalence rate of chronic calculus cholecystitis found in this study was 6.9%. There was a relationship between chronic calculus cholecystitis and age group, sex, DM, BMI group, Thyroid disease and Hypertension. The prevalence of chronic calculus cholecystitis was more in females compared to males (9.0% vs. 4.2%). Conclusion: female gender, diabetes and obesity are significantly associated factors in the development of gallstones. Thus, understanding the gallstones pathogenesis would result in life style modifications and weight loss which would decrease the rates of the disease.