Abstract

BackgroundChronic kidney disease (CKD) is a progressive disease that causes a permanent impairment of renal function and premature mortality. The associated prognosis may result in serious psychological distress to the affected individual. However, there are limited data on the psychological correlates, and in particular depression, in Chinese CKD patients. This study aimed to examine the prevalence of depression, as well as the influence of other psychosocial factors on depression, among Taiwanese CKD patients.MethodsWe used a cross-sectional research design to recruit 270 CKD patients who were not undergoing dialysis treatment at a hospital in southern Taiwan during 2011. The structured questionnaire used in this study gathered information on respondent demographic and disease characteristics, and information obtained from the Taiwanese Depression Questionnaire. Factors associated with depression were examined by a multiple logistic regression analysis.ResultsThe crude and age-standardized prevalence of depression were 22.6% and 20.6%, respectively. Those who had sleep disturbances, reported having no religious beliefs, followed no regular exercise regimen, and were diagnosed with stage III or above CKD demonstrated a significantly higher risk of depression.ConclusionOur findings are beneficial to healthcare providers, as they identify both the prevalence of depression and several of its correlates. By identifying CKD patients with a higher risk of depression, healthcare providers may be better able to ensure the provision of appropriate rehabilitation to this population.

Highlights

  • Chronic kidney disease (CKD) is a progressive disease that causes a permanent impairment of renal function and premature mortality

  • 61 individuals met the criteria for depression based on the Taiwanese Depression Questionnaire (TDQ) total score of ≥19, which translates to a crude prevalence of 22.6% (61/270)

  • This study found that the crude and age-adjusted prevalence of depression were 22.6% and 20.6%, respectively, revealing that one out of five CKD patients met the criteria for depressive disorders

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Summary

Introduction

Chronic kidney disease (CKD) is a progressive disease that causes a permanent impairment of renal function and premature mortality. There are limited data on the psychological correlates, and in particular depression, in Chinese CKD patients. Based on a report by the United States Renal Data System published in 2007, Taiwan had the highest incidence and prevalence rate of ESRD patients globally, with 415 and 2288 per million populations, respectively [2]. Wen and colleague [4] found that CKD patients had an 83% higher rate of all-cause mortality and were twice as likely to die from cardiovascular disease. One cause of concern was that depression elevated the length of hospitalization by 30% [9], and more than doubled the likelihood of mortality in ESRD patients with depression compared to those with ESRD only [8]. A study demonstrated that depression in CKD patients, who were not receiving dialysis treatment, was linked to a 86% higher risk of adverse events including death, early dialysis initiation or hospitalization risk [10], suggesting that depression is a matter of great concern during the routine care of CKD patients

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