Prevalence and Contributing Factors of Meconium Stained Amniotic Fluid Among Women Delivered at St Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia

Hana Abera Hailemariam ,Frehiwot Nigusse

doi:10.7176/jmpb/67-01

Abstract

Background : The incidence of meconium-stained amniotic fluid during labor were considered as an indicator of unpleasant condition for the delivery outcomes which leads to mild to severe respiratory problem, which contributed to perinatal and neonatal morbidity and mortality. Objective: To assess the prevalence of meconium stained amniotic fluid and its contributing factors among mothers who delivered at. St. Paul´s Hospital Millennium Medical College. Methods : Hospital based cross-sectional study design was implemented at St. Paul´s Hospital Millennium Medical College from June 26 – July 24,2019. The study respondents were chosen by using systematic random sampling methods. Chart review together with structured interview was implemented to gather the data. Data was entered and analyzed by SPSS versions 20. Both descriptive & analytical statistics were calculated. Statistical significance was measured at P<0.05 and the degree of association were assessed by using adjusted odds ratio. Result: A total of 248 mothers were enrolled in the study with a response rate of 100%.The prevalence of meconium stained amniotic fluid was found 30(12.1%) with [95%CI = 8.1-16.5. Women whose premature rapture of membrane [AOR=7.6, 95%C1=2.525-23.00], preeclampsia [AOR=5.4, 95%C1=1.579-19.145, prolonged premature rapture of membrane [AOR=5.1, 95%C1=1.221-22.122], duration of labor >12hrs [AOR=5.1, 95%C1=1.221-22.122], prolonged labor [AOR = 3.0, 95%CI=1.075-8.857] were associated with meconium stained amniotic fluid in this study . Conclusion: The finding concludes that meconium stained amniotic fluid was common problem which impose adverse condition to the fetus and newborn. And it is related to maternal factors such as preeclampsia, length of labor, Prolonged Premature Rupture Of Membrane (PPROM), Premature Rupture Of Membrane (PROM) and prolonged labour which increase the incidence of meconium stained amniotic syndrome. Keywords: Meconium, Meconium stained amniotic fluid, St Paul Hospital Millunium Medical College. DOI: 10.7176/JMPB/67-01 Publication date: August 31 st 2020

Highlights

Back ground Meconium stained liquor (MSL) is the presence of meconium in the uterus during intranatal period.[1]
Major Maternal and fetal factors which leads to Meconium stained amniotic fluid (MSAF) include hypertension, gestational diabetes mellitus, maternal chronic respiratory or cardiovascular diseases, post term pregnancy, preeclampsia, eclampsia, oligohydramnios, Intra uterine growth retardation and poor bio physical profile.[3]
MSAF results long and short-term delivery outcomes, which increased the need of neonatal assistance, due to the adverse outcome such as respiratory distress, lower Apgar score, meconium aspiration syndrome, neonatal sepsis and lung disease.2, 4The effects of MSAF is posing a threat to the fetus or the neonate, and lead to serious maternal complications include amniotic fluid embolism and puerperal endometritis.[5, 6]

Summary

Introduction

Back ground Meconium stained liquor (MSL) is the presence of meconium in the uterus during intranatal period.[1]. MSAF results long and short-term delivery outcomes, which increased the need of neonatal assistance, due to the adverse outcome such as respiratory distress, lower Apgar score, meconium aspiration syndrome, neonatal sepsis and lung disease.2, 4The effects of MSAF is posing a threat to the fetus or the neonate, and lead to serious maternal complications include amniotic fluid embolism and puerperal endometritis.[5, 6]. The incidence of meconium-stained amniotic fluid during labor were considered as an indicator of unpleasant condition for the delivery outcomes which leads to mild to severe respiratory problem, which contributed to perinatal and neonatal morbidity and mortality. Methods: Hospital based cross-sectional study design was implemented at St. Pauls Hospital Millennium Medical College from June 26 – July 24,2019.

Objectives

Methods

Findings

Conclusion