Prevalence and comorbidities associated with hidradenitis suppurativa in Korea: a nationwide population-based study.

Abstract

The prevalence of hidradenitis suppurativa (HS) in Asia is unknown. The associations between HS and other autoimmune disorders have rarely been reported. We sought to determine the prevalence of and diseases associated with HS using the National Health Insurance (NHI) database. We examined Korean NHI claim database data from 2007 to 2016. We enrolled all patients with HS and age- and sex-matched control subjects without HS. We estimated the period prevalence of HS and associated comorbidities in Korea. We identified 28516 patients with HS (61.3% males and 38.7% females). The period prevalence rate was 0.06%, 55.8 patients (95% confidence interval 55.1-56.4) per 100000 persons, and the female-to-male ratio was 1:1.6. HS patients were at significantly increased risk of rheumatoid arthritis, ankylosing spondylitis, type 1 diabetes, ulcerative colitis, type 2 diabetes, hypertension, hyperlipidaemia, acne conglobata, pilonidal cysts, psoriasis, pyoderma gangrenosum, alopecia areata and vitiligo. The overall prevalence of HS in Korea was lower than that in Western populations, and male patients predominated.