Abstract
Introduction: Chronic kidney disease (CKD) has become a major health concern on a global scale, and its impact is also significant in Sri Lanka. Diabetes mellitus and hypertension are identified as the main causes of CKD in Sri Lanka. Chronic kidney disease of unknown origin (CKDu) has undeniably surfaced as a substantial factor in the prevalence of CKD in recent decades, notably in specific geographic areas worldwide. Methods: Over a course of three months, a descriptive cross-sectional study was carried out at the outpatient clinics of the National Hospital of Sri Lanka to describe the socio-demographic factors related to CKD and to understand the aetiological factors of the disease within CKD patients attending the clinics.Results: The study involved 387 CKD patients, with an average age of 53 years. Males accounted for 62.8%. Of total participants, CKD Stage V with or without regular dialysis consisted of 26.5% and transplant patients consisted of 26.8%. Most (88.1%) patients were from the western province while 11.9% were from other provinces. The prevalence of CKD secondary to diabetes mellitus was 35.9% followed by hypertensive kidney disease (31.3%). The most common aetiology for CKD in the western province was diabetes mellitus (37.2%) followed by hypertension (31.5%). The prevalence of CKDu was 7.9% in the western province and 13.0 % in other regions. Diabetes mellitus (p< .001) and glomerulonephritis (p< .001) were significantly associated with age groups above and below 40 years.Conclusion: This study highlights diabetes and hypertension as the predominant causes of CKD among patients in both the western province and other provinces of Sri Lanka. It also highlights the heightened prevalence of hypertensive kidney disease in the young population compared to previous studies.
Published Version
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