Abstract

Purpose of investigation: To evaluate the risk factors of gestational diabetes mellitus (GDM) to decrease maternal and neonatal complications. Materials and Methods: This cross-sectional study was performed on parturients in the single-maternity hospital of Sabzevar, Iran. All of them had been screened for GDM in the first trimester and 24-28 weeks of gestational age. The prevalence and risk factors of GDM were assessed by STATA. Results: From 609 women, GDM was found in 28 persons (4.6%). Maternal age and body mass index (BMI), multiparity, family history of diabetes, prior GDM, hirsutism, hypertension, and hypothyroidism had significant association with GDM. Opiate addiction did not show any relation. Previous birth of preterm or handicapped baby was significantly higher in GDM group; however previous abortion, stillbirth, and birth of large baby showed no significant relation with GDM. Conclusions: Providing a risk assessment checklist is very helpful for prevention and early detection of GDM.

Highlights

  • Gestational diabetes mellitus (GDM) is defined as glucose intolerance with first onset or first recognition during pregnancy

  • Several methods have been applied for the screening of GDM like taking 75 or 100 grams of glucose which have certainly influenced on different incidence rates reported worldwide until 2013 when World Health Organization (WHO) accepted the method of International Association of Diabetes and Pregnancy Study Groups (IADPSG) and the applied tests became to some extent unified

  • Previous birth of preterm or handicapped baby was significantly higher in GDM group (p = 0.039 and p =0.006); previous abortion, stillbirth and birth of large baby showed no significant relation with GDM (p =0.87, p = 0.487, p =0.234, respectively)

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Summary

Introduction

Gestational diabetes mellitus (GDM) is defined as glucose intolerance with first onset or first recognition during pregnancy. Detection of GDM is very important because it can induce maternal adverse effects like polyhydramnios, preeclampsia, increased caesarean section, infection, and other postpartum complications in current pregnancy; it can be a main risk factor for future obesity, type 2 diabetes, and hypertension in mothers [5-7]. Their offspring are at risk of macrosomia, prolonged labor, shoulder dystocia, bone fracture, erb pulsy, hypoglycemia, hypocalcemia, hypomagnesemia, hyperbilirubinemia, respiratory distress syndrome, polycythemia, perinatal mortality, and obesity and type 2 diabetes in adulthood [6, 8-10]. Some contributor factors have been discussed for GDM including maternal old age, obesity, prior GDM, family history of diabetes, high parity, and past history of cesarean section, abortion, stillbirth, and childbirth with macrosomia or malformation [3, 6, 11, 12]

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