Abstract
Two hundred urine samples were collected from patients attending diabetic clinic at the Federal Medical Centre Gombe (FMCG). The samples were cultured on nutrient agar and the isolates obtained were Gram-stained, subjected to biochemical tests to confirm their identities. All the 200 samples were found to contain Gram negative organisms. Of the 200 gram negative isolates obtained, 111(55.5%) were found to be positive for E. coli while the remaining, 89(44.5%) were found to be negative for E. coli but positive for other enteric gram negative rods(Enterobacteriaceae). Female diabetic patients recorded higher incidence of 85(77%) than their male counterparts of 26(23%). Antimicrobial susceptibility testing was carried out against the isolated E. coli using Kirby-Bauer (1966) method and shows the activity of only members of Aminoglycosides, streptomycin and Gentamycin as moderately sensitive and highly sensitive respectively. Other antibiotics proved inactive, to which the E. coli became resistant, and these include Septrin, chloramphenicol, quinolones (Sparfloxacin, ciprofloxacin, Peploxacin and Tarivid) and augmentin (Maxi high profile Gram negative antibiotics).
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