Abstract
BackgroundUrinary Tract Infections (UTI) are one of the most common bacterial infections in routine clinical practice. It is also the most common nosocomial infection in many hospitals. Study of causative agents and their Antimicrobial sensitivity pattern are important factors helping formulating antibiotic policy. Generally, the most common uropathogen is Escherichia coli. Tertiary care hospitals, catering for already partially treated or maltreated patients as major chunk, may have different etiological agents and sensitivity pattern. ObjectivesTo study prevalence of pathogens causing UTI among patients coming to a tertiary care hospital, along with their antibiotic sensitivity pattern. MethodsThis study was undertaken for a period from July 2017 to Nov’2018 at Department of Microbiology, Vivekananda Polyclinic Institute of Medical sciences, Lucknow, India. Clean catch mid-stream urine samples were collected from all suspected UTI patients of various departments. The urine samples were processed for culture and Antibiotic susceptibility testing according to standard guidelines. ResultsA total of 10,171 urine samples were processed for urine culture and sensitivity, Total 1,728 samples were found to be positive for bacterial infection (amounting almost 17% positivity). For the ease of analysis, positive isolates (n = 1728) were further categorized into isolates obtained from outdoor patients (OPD; n = 824), from indoor patients (IPD; n = 747) and from pediatric patients (n = 157). Escherichia coli was the most frequently isolated urinary pathogen in all categories. Enterococcus and Candida were significantly isolated more in IPD patients. ConclusionSensitivity pattern was also different in all categories. Tertiary care hospital has difference in prevalence of etiological agents and their sensitivity pattern.
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