Prevalence and antibiotic sensitivity pattern of pseudomonas aeruginosa isolates from respiratory samples, pus samples and body fluids in a tertiary care hospital, Kashmir

Abstract

Pseudomonas aeruginosa has established itself as an important pathogen because of its ability to survive the hostile environments and causing life threatening infections. This gram negative bacillus has acquired resistance to different classes of antimicrobials thereby increasing the morbidity and mortality. In the present study we aim to analyze the rate of isolation of this opportunistic pathogen from various body fluids as well as respiratory and pus samples and the antimicrobial resistance profile of all these isolates. Standard microbiological techniques were used for its isolation, culture and identification followed by the antimicrobial sensitivity testing using disk diffusion method. Of the 3530 samples received over a two year period, the presence of Pseudomonas aeruginosa was detected in 71 samples (9.16%). A higher resistance was observed for ceftriaxone, ceftazidime and ciprofloxacin but a considerable number of isolates were sensitive to carbapenems. Most of the isolates were sensitive to polymyxin B. Keywords: Pseudomonas aeruginosa, Multidrug resistant (MDR), Extensively drug resistant (XDR), Outpatient department (OPD), Inpatient department (IPD).