Prevalance and distribution of candidia species from diabetic foot ulcer in tertiary care centre, Jamnagar, Gujarat

Binita J Aring,Pushpa R Kateshiya,Dipali Maganbhai Gavali

doi:10.18231/j.pjms.2021.048

Binita J Aring, Pushpa R Kateshiya + Show 1 more

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https://doi.org/10.18231/j.pjms.2021.048

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Abstract

Diabetes Mellitus is a chronic disease which may cause diabetic foot ulcer, which is a major cause of morbidity and mortality, it may also lead to foot amputation due to gangrene, and may cause cellulitis, abscess etc.To study prevalence of candidiasis in diabetic foot ulcer in a tertiary care centre, Jamnagar.32(10.66%) isolates that were recovered from wound discharge samples (300 samples tested) from November 2017 to September 2018. All isolates were visualized under direct microscopy, cultured, & sugar assimilation tests were performed.Amongst 300 samples 32(10.66%) were positive for fungal culture, in which major isolates was C. albicans (50%), C. tropicalis (18.75%), C. dubliniensis (9.37%), C.krusei (9.37%), C. glabrata (6.25%), C. parapsilosis (6.25%).This study shows that in Diabetic foot ulcer most common fungal pathogens were C. Albicans, C. tropicalis, C. dubliniensis, etc. Early identification of organism can help in early treatment and early recovery.

Highlights

Diabetes Mellitus is a chronic disease which may cause diabetic foot ulcer, which is a major cause of morbidity and mortality, it may lead to foot amputation due to gangrene, and may cause cellulitis, abscess etc
1 Diabetes mellitus have major 3 types (I) Type I: Insulin dependent diabetes mellitus (IDDM), where pancreases produces decreased amount of insulin (Insulin deficiency). (II) Type II: Non- Insulin dependent diabetes mellitus (NIDDM) or Adult diabetes mellitus, where body cells do not respond to insulin (Insulin Resistance). (III) Type III: Gestational Diabetes occurs in pregnant women due to high sugar level
Diagnosis of a yeast infection is done by direct microscopic examination, culturing, further diagnosis done with serological, molecular methods and other newer rapid diagnostic tests are available like Flurogenic Tests, Platelia Candida antigen test, Rapid trehalose assimilation test, Cand Tec Ramco labs. 9

Summary

Introduction

Diabetes Mellitus is a chronic disease which may cause diabetic foot ulcer, which is a major cause of morbidity and mortality, it may lead to foot amputation due to gangrene, and may cause cellulitis, abscess etc. Results: Amongst 300 samples 32(10.66%) were positive for fungal culture, in which major isolates was C. albicans (50%), C. tropicalis (18.75%), C. dubliniensis (9.37%), C.krusei (9.37%), C. glabrata (6.25%), C. parapsilosis (6.25%). Conclusion: This study shows that in Diabetic foot ulcer most common fungal pathogens were C. (III) Type III: Gestational Diabetes occurs in pregnant women due to high sugar level. Among these type 90% cases were Type II Diabetes mellitus. In non- traumatic lower limb amputation most common cause was diabetic foot ulcer. Due to the lack of mycological importance, fungal infections were ignored to be a cause of diabetic ulcer

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