Abstract

The goals of the meticulous selection of patients withhepatocellular carcinoma (HCC) for liver transplanta-tion (LT) are to minimize the incidence of tumor recur-rence after transplantation and to improve patients’survival. Tumor invasion into vascular structures is aknown risk factor for tumor recurrence after LT. Mac-rovascular invasion, which is defined as the presenceof a tumor thrombus in a hepatic or portal vein, canbe detected on preoperative cross-sectional imaging. Itis considered an absolute contraindication to LT. Con-versely, microvascular invasion (MVI) by definitioncan be definitively diagnosed only by histopathology.Several studies have shown that MVI is associatedwith HCC recurrence within 1 year of transplanta-tion.

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