Abstract
Objective: To evaluate retrospectively pre-term induction; with Prostaglandin (PG) E 2-gel and i.v. oxtytocin, respectively. Methods: Fifty pre-term women with a gestational age between 28+0 and 36+6 and medical indications for labor induction were compared with the two next induced at term and post-term. The obstetric end points were numbers of PGE 2-gel applications, failed inductions, instrumental delivery and heavy bleeding after partus (>1000 ml). The neonatal outcome was registered as operative delivery for fetal distress (ODFD) or Apgar score <7 at 5′. Results: The number of PGE 2-gel applications did not differ. The duration of labor was shorter in the pre-term group ( P=0.043). A five-fold higher risk of heavy postpartum bleeding (>1000 ml) was noticed in the post-term group compared to the pre-term. The incidence of low Apgar scores were similar in the three groups. Conclusions: Safe vaginal labor induction and delivery can be anticipated pre-term with PGE 2-gel.
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