Abstract

A 50-year-old man was admitted for evaluation of syncope. Clinically, he had an irregular pulse and an ejection systolic murmur loudest at the left sternal border. Transthoracic echocardiography revealed hypertrophic cardiomyopathy (HCM) with midventricular obstruction and apical aneurysm with maximum pressure gradient greater than 74 mm Hg. Coronary angiogram showed normal coronary arteries. Left ventriculogram using 4 Fr pigtail catheter via right radial approach showed nearly total obliteration of left ventricular (LV) cavity at the midventricular level (arrows) with apical aneurysm (Fig. 1A and B). Pressure tracing from LV apex to the aorta showed a significant systolic pressure gradient within the left ventricular cavity (Fig. 1C). The day after cardiac catheterization, he complained of palpitation and mild dizziness and an electrocardiogram showed sustained monomorphic ventricular tachycardia (VT) of LV apical origin. The final diagnosis was HCM with midventricular ob struction complicated by VT. HCM is an extremely heterogeneous disease. In a patient with

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