Abstract
Keeping pressure gradient is an excellent approach to prevent the reveal of airflow direction and cross infection in manufacturing circumstances of pharmaceutical cleanrooms, thus how to keep cleanroom’s pressure is critical. In the paper, we study a positive pressure pharmaceutical cleanroom system which is composed by a cleanroom and an airlock. We divide the system’s disturbances into step disturbance, ramp disturbance and sine wave disturbance. We design its pressure gradient control strategies, including CAV control, PID control and active-disturbance-rejection-control. We build the system’s model and make simulations based on Matlab/Simulink software platform. Results show that active-disturbance-rejection-control algorithm has good capabilities for shorter responding time and lower overshot of the pressure gradient. The results reveal that active-disturbance-rejection-control method has good control performances in responding time, accuracy and disturbance rejection.
Highlights
With the fast development of precision manufacturing and cleaner production, the number and scale of cleanrooms increase rapidly over the world
We study a positive pressure pharmaceutical cleanroom system which is composed by a cleanroom and an airlock
We propose to use a new control method to keep setting and avoid cross infection
Summary
With the fast development of precision manufacturing and cleaner production, the number and scale of cleanrooms increase rapidly over the world. One problem is there are many disturbances in cleanroom system, such as open and close of the door, the periodic change between occupied time and unoccupied time, and so on These disturbances can cause the pressure difference frequent vibration, long responding time and big overshot [8]. Another problem is that almost all cleanrooms have the high design pressure difference for maintaining manufacturing circumstance, this causes huge energy waste [9]. A good method with strong disturbance rejection and high precision in controlling pressure difference in cleanroom can attract researcher’s attention. Has advantages in responding time and disturbance rejection, and good capabilities in rejecting disturbance and control precision
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