Abstract
Static and dynamic exercise are accompanied by increases in arterial blood pressure, heart rate and sympathetic nerve activity. It is thought that the activation of the muscle metaboreflex is one of major mechanisms for evoking the pressor responses during heavy intensity exercise [1]. It has been shown that the arterial baroreflex buffers the muscle metaboreflex-mediated pressor responses [2]. However, it is unknown whether the carotid baroreflex modifies muscle metaboreflex function in humans. Therefore, the purpose of this study was to investigate the effects of unloading of carotid baroreceptors on threshold and gain of the muscle metaboreflex in humans.
Highlights
Static and dynamic exercise are accompanied by increases in arterial blood pressure, heart rate and sympathetic nerve activity
The carotid baroreceptors were unloaded by 0.1 Hz sinusoidal neck pressure during the third min of ischemia
The gains of the muscle metaboreflex that were estimated as maximum rate of changes in hemodynamic values to change in work amount were not different between these two conditions (gain for mean arterial blood pressure (MAP): 4.9 (0.5) vs. 4.4 (0.5) mmHg.kg.s-1.100, for total vascular resistance (TVR): 1.3 (0.3) vs. 1.3 (0.2) mmHg.L-1.min-1.kg.s-1.100)
Summary
Static and dynamic exercise are accompanied by increases in arterial blood pressure, heart rate and sympathetic nerve activity. It is thought that the activation of the muscle metaboreflex is one of major mechanisms for evoking the pressor responses during heavy intensity exercise [1]. It has been shown that the arterial baroreflex buffers the muscle metaboreflex-mediated pressor responses [2]. It is unknown whether the carotid baroreflex modifies muscle metaboreflex function in humans. The purpose of this study was to investigate the effects of unloading of carotid baroreceptors on threshold and gain of the muscle metaboreflex in humans
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
