Abstract
Alzheimer's disease increases with age with an annual incidence rate of more than 1000 new cases for 100000 over the age of 80.1 We have shown that acetylcholinesterase (AChE) activity, a marker of the cholinergic system, significantly decreased in the cerebral cortex of patients with Alzheimer's disease compared with age-matched normal volunteers, with N[11C]methyl-4-piperidyl acetate ([11C]MP4A) and positron emission tomography (PET).2 If ageing is a risk factor for Alzheimer's disease, activity of cholinergic enzymes might also decrease with ageing.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
