Preservation of Mimosa tenuiflora Antiaflatoxigenic Activity Using Microencapsulation by Spray-Drying.

Christopher Hernandez,Laura Cadenillas,Céline Mathieu,Vanessa Durrieu,Jean-Denis Bailly

doi:10.3390/molecules27020496

Abstract

Mimosa tenuiflora aqueous extract (MAE) is rich in phenolic compounds. Among them, condensed tannins have been demonstrated to exhibit a strong antioxidant and antiaflatoxin B1 activities in Aspergillus flavus. Since antioxidant capacity can change with time due to environmental interactions, this study aimed to evaluate the ability of encapsulation by spray-drying of Mimosa tenuiflora aqueous extract to preserve their biological activities through storage. A dry formulation may also facilitate transportation and uses. For that, three different wall materials were used and compared for their efficiency. Total phenolic content, antioxidant activity, antifungal and antiaflatoxin activities were measured after the production of the microparticles and after one year of storage at room temperature. These results confirmed that encapsulation by spray-drying using polysaccharide wall materials is able to preserve antiaflatoxin activity of Mimosa tenuiflora extract better than freezing.

Highlights

Aflatoxin B1 (AFB1) is a worldwide public health issue due to its carcinogenic, immunotoxic and mutagenic properties in humans and animals [1,2]
We evaluated the impact of encapsulation process on the antioxidant, antifungal and antiaflatoxigenic effects of Mimosa tenuiflora aqueous extract (MAE)
We demonstrated that polysaccharide microparticles were able to preserve anti-AFB1 activity of MAE more efficiently than after storage at −20 ◦ C

Summary

Introduction

Aflatoxin B1 (AFB1) is a worldwide public health issue due to its carcinogenic, immunotoxic and mutagenic properties in humans and animals [1,2]. This toxic fungal metabolite is produced by several species of Aspergillus, mostly grouped in the Flavi section [3]. Aflatoxins are thermophilic species and AFB1 is a major contaminant in regions with hot climate. Due to the toxicity and especially to the carcinogenic property of AFB1, many countries have set up regulation in different foods to limit consumers’ exposure [8]

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